Willow: ADME prediction software for medicinal chemists
Identify potential liabilities earlier, investigate metabolism, and evaluate design decisions in real time.
Move from prediction to decision with Willow
Willow is the first software module available through Canopy, MFI’s growing chemistry-first decision intelligence platform.
Designed for ADME prediction with depth in metabolism and Cytochrome P450 (CYP) enzyme activity, Willow brings molecular structures, predicted properties, metabolism calculations, and scientific context together in one environment. Willow enables medicinal chemists to identify potential liabilities earlier, examine the evidence behind a result, and determine what deserves attention next.
See the prediction
Draw or edit a molecule and see its predicted properties update in real time. View 2D and 3D structures alongside ADME and other property results, allowing you to explore ideas and identify potential risks before committing experimental resources.
Understand the result
Investigate predicted sites of metabolism, evaluate multiple CYP enzymes, and examine structure-based results in 3D. Move between the information relevant to your question without crowding the workspace.
Decide what comes next
Pin a lead or reference compound, then design and assess new molecules against it. See how predicted properties change as you explore ideas, helping you determine which directions deserve further investigation.
Designed as a companion for medicinal chemists
Willow keeps molecular structures, predicted properties, metabolism results, and 3D views within one flexible environment. Open, close, and rearrange information as the scientific question changes, keeping the evidence you need available without unnecessary clutter.
See Willow in action
Explore how Willow can support the decisions your team is making about molecular design, potential liabilities, and what to investigate next.
Interested in the science behind Willow?
Read our latest preprint exploring advances in metabolism prediction and the scientific foundations behind the Willow platform.