About Us

Molecular Forecaster Inc. was founded in 2010 by Dr. Eric Therrien and Prof. Nicolas Moitessier as a spin-off from McGill University. In 2016, Dr. Joshua Pottel took over as President. The company has an exclusive agreement with McGill University for the distribution and use of the FORECASTER and VIRTUAL CHEMIST Platforms - including the FITTED docking program, the IMPACTS site of metabolism prediction protocol, and the ACE asymmetric catalysis simulation algorithm.

Molecular Forecaster Inc. is a leading scientific company that distributes the FORECASTER and VIRTUAL CHEMIST platforms and offers contract research services. We are a team of specialized scientists with work experience in medicinal, synthetic, and computational chemistry.

Ultimately, we are experimentalists with expertise in molecular modeling. We leverage our knowledge of chemical principles to solve chemical and biochemical problems virtually; we develop our own high accuracy programs with unique, customizable features.

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Management Team


Joshua Pottel, Ph.D.

President

Dr. Pottel is President of Molecular Forecaster. He completed his B.Sc. in chemistry at McGill University in 2011 along with a minor in computer science. Under the supervision of Nicolas Moitessier, he obtained his Ph.D. from McGill, focusing his research on software development in chemo- and bioinformatics. He followed this with postdoctoral research as an NRSA fellow at UCSF with Dr. Brian Shoichet using computational techniques to rationally predict relevant polypharmacology followed by confirmatory in-vitro assays.

In his academic career, he has received provincial and federal prizes from the Quebec, Canadian, and American governments. He has authored over a dozen peer-reviewed publications and is a co-inventor of the VIRTUAL CHEMIST platform.

Nicolas Moitessier, Ph.D.

Vice-President

Dr. Moitessier is Associate Professor at McGill University and co-founder of Molecular Forecaster. He received his undergraduate training and his Ph.D from Université Henri Poincaré-Nancy I (France) under the guidance of Dr. Yves Chapleur within the Groupe SUCRES (UMR CNRS 7565). In 1998, he moved to Montréal where he joined Prof. Stephen Hanessian group as a post-doctoral fellow. In 2001, he moved back to Nancy to start an academic career (Chargé de Recherche, CNRS) then back to Montréal in 2003 (Assistant Professor, McGill University).

His current interests integrate computational chemistry and organic/medicinal chemistry, spanning from software development to sugar chemistry. In 2008, he received the first Reginald Fessenden Professorship in innovation for the development of the Forecaster platform in drug discovery then the Reginald Fessenden Prize in Innovation for the Virtual Chemist platform. In 2009, he was awarded the AstraZeneca Award in Chemistry. He is author of over 80 peer-reviewed publications and co-inventor of 2 patents and 4 reports of invention.

Nathalie Desfossés, CHRP, CIRC

Partner

Nathalie Desfossés received a BSc from Université de Montréal and specialized in human resources. She first joined the city of Saint-Lambert then moved to large private companies (Laurentian Bank, Transat AT). More recently, she moved to VA Transport, a large transportation company, where she has been the HR director.

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Founders


Nicolas Moitessier, Ph.D.

Co-founder

Dr. Moitessier is Associate Professor at McGill University and co-founder of Molecular Forecaster. He received his undergraduate training and his Ph.D from Université Henri Poincaré-Nancy I (France) under the guidance of Dr. Yves Chapleur within the Groupe SUCRES (UMR CNRS 7565). In 1998, he moved to Montréal where he joined Prof. Stephen Hanessian group as a post-doctoral fellow. In 2001, he moved back to Nancy to start an academic career (CNRS) then back to Montréal in 2003 (McGill University)

Eric Therrien, Ph.D.

Co-founder

Dr. Therrien is co-founder of Molecular Forecaster. He has over 11 years of experience in medicinal, organic and computational chemistry. Dr. Therrien received his Ph.D. in chemistry from the Université de Montréal and post-doctoral training from McGill University.

He served as President of Molecular Forecaster inc. for 6 years and is now pursuing other opportunities.

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Acknowledgements


Over the last years, the development of FITTED, IMPACTS, ACE and all the other tools of FORECASTER has been funded by ViroChem Pharma (research grants), the Canadian Institutes for Health Research (CIHR Operating grants), AstraZeneca and the Natural Science and Engineering Research Council (NSERC discovery grant). In addition, the “Ministère du Développement Economique, de l'lnnovation et de l'Exportation du Québec" has recognized the potential of our drug discovery platform by funding the development and the commercialization as part of a program called "Soutien à la maturation technologique".

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The Team of Developers


This software would have not been available without the contribution of outstanding people.

Pablo Englebienne    (2003-2009)
Christopher R. Corbeil    (2005-2009)
Jeremy Schwartzentruber    (2007)
Eric Therrien    (2008-2016)
Nathanael Weill    (2010-2011)
Valerie Campagna-Slater    (2010-2011)
Andy Arrowsmith    (2009-2011)
Joshua Pottel    (2011-present)
Zhaomin Liu    (2011-2017)
Anna Tomberg    (2013-2017)
Matthieu Moitessier    (2013-present)
Mihai Burai-Patrascu    (2015-present)
Stephen J. Barigye    (2015-present)
Wanlei Wei    (2016-present)
Jiaying Luo    (2016-present)
Candide Champion    (2017-present)

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